Two Sesquilignans from the Wood of Abies Marocana

Abst rac t -From the chloroform extract of the wood of Abies rnarocana, consisting mainly of lignans, the acetoxyl derivatives of the new sesquilignans, 4,4",7",9,9"-pentahydroxy-3,3',3"-trimethoxy-4',8":7,9'-bis-epoxy-8,8'-sesquineolignan and 4•4"•7"•9•9'•9"-hexahydr•xy-3•3'•3••-trimeth•xy-4'•8"-ep•xy-8•8'-sesquine••ignan were isolated; the trivial names, sesquimarocanols A and B, were subsequently assigned, respectively. Also, (9'R)-9'-hydroxylariciresinol tetraacetate, (7'R)-7'-hydroxylariciresinoi tetraacetate and sesquipinsapol B pentaacetate, which had previously only been found in A. pinsapo, were isolated, together with some well known compounds. The new structures were established by spectroscopic methods. Certain cytotoxic activity assays were performed on the new compounds.